PDTM-46. POLIOVIRUS RECEPTOR (CD155) EXPRESSION IN PEDIATRIC BRAIN TUMORS MEDIATES ONCOLYSIS OF MEDULLOBLASTOMA AND PLEOMORPHIC XANTHOASTROCYTOMA

INTRODUCTION: Poliovirus oncolytic viral immunotherapy is a putatively novel approach to treat both low grade and malignant pediatric brain tumors. However, the expression of the poliovirus receptor (PVR), CD155, on a variety of pediatric brain tumors and its ability to infect, propagate, and lyse p...

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Publicado no:Neuro Oncol
Main Authors: Thompson, Eric, Brown, Michael, Dobrikova, Elena, Ramaswamy, Vijay, Taylor, Michael, McLendon, Roger, Chandramohan, Vidya, Bigner, Darell, Gromeier, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217466/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.885
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