DIPG-04. INHIBITION OF AXL SENSITIZES DIFFUSE INTRINSIC PONTINE GLIOMA TO CYTOTOXIC THERAPIES

Diffuse intrinsic pontine glioma (DIPG) is an incurable type of pediatric brainstem cancer that is thought to originate from primitive neural stem cells, and is characterized by the frequent presence of mutations in histone 3 genes. Biopsy studies have shown that a large subset of DIPG possesses a m...

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Publicado en:Neuro Oncol
Main Authors: Meel, Michaël, de Gooijer, Mark, Zwaan, Kenn, Waranecki, Piotr, Breur, Marjolein, Buil, Levi, Lagerweij, Tonny, Wedekind, Laurine, Twisk, Jos, Koster, Jan, Hashizume, Rintaro, Raabe, Eric, Carcaboso, Ángel Montero, Bugiani, Marianna, van Tellingen, Olaf, van Vuurden, Dannis, Kaspers, Gertjan, Hulleman, Esther
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Abstracts
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012142/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.098
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