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EAPH-12. CELASTROL INDUCED DEGRADATION OF FANCD2 SENSITIZES PEDIATRIC HIGH-GRADE GLIOMA TO THE DNA-CROSSLINKING AGENT CARBOPLATIN

Pediatric high-grade gliomas (pHGG) are the leading cause of cancer-related death during childhood. Due to their diffuse growth pattern, difficult to reach location during surgery and position behind the blood-brain barrier (BBB), prognosis of pHGG has barely improved, despite decades of research. C...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Metselaar, Dennis, Meel, Michaël, Waranecki, Piotr, Zwaan, Kenn, van Vuurden, Dannis, Kaspers, Gertjan, Hulleman, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012777/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.181
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