TBIO-22. A NOVEL PEDIATRIC IDH1 MUTANT GLIOBLASTOMA CELL LINE AND XENOGRAFT MODEL

The isocitrate dehydrogenase-1 (IDH1) mutation serves as a hallmark for secondary high-grade gliomas, occurring in over 75% of all secondary glioblastomas (GBM) in adults. IDH1 mutations in pediatric high-grade gliomas are much rarer, and its role is still largely unknown. The lack of biologically r...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Metselaar, Dennis, Meel, Michaël, Waranecki, Piotr, Zwaan, Kenn, Poddighe, Pino, van Vuurden, Dannis, Kaspers, Gertjan, Hulleman, Esther
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012797/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.710
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