ATRT-19. PRECLINICAL EFFICACY OF COMBINED INHIBITION OF MEK AND MELK IN ATYPICAL TERATOID/RHABDOID TUMORS

Atypical teratoid/rhabdoid tumors (AT/RT) are highly malignant tumors of the central nervous system occurring predominantly in young children. Currently, the only curative therapeutic option consists of surgery combined with intensive chemo- and radiotherapy, often leading to severe long-term sequel...

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Publicado no:Neuro Oncol
Main Authors: Meel, Michaël, Navarro, Miriam Guillén, de Gooijer, Mark, Waranecki, Piotr, Petersen, Naomi, van Vuurden, Dannis, Kaspers, Gertjan, Hulleman, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012843/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.017
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