ATRT-05. PRECLINICAL EFFICACY OF RADIATION-FREE TREATMENT OF ATYPICAL TERATOID/RHABDOID TUMORS BY COMBINED MEK AND MELK INHIBITION

Atypical teratoid/rhabdoid tumors (AT/RT) are highly malignant tumors that occur both in- and outside the central nervous system, predominantly in young children. Although therapeutic interventions, combining surgery with intensive chemotherapy and conformal radiotherapy, have shown curative potenti...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Meel, Michaël H, Guillén-Navarro, Miriam, de Gooijer, Mark C, Waranecki, Piotr, de Winter, Marcel P, van Vuurden, Dannis G, Kaspers, Gertjan JL, Hulleman, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474975/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.004
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