DIPG-55. TARGETING SENESCENT CELLS WITH ABT-263 ENHANCES CELL DEATH INDUCED BY BMI1 INHIBITION AND IONIZING RADIATION IN DIPG

Ionizing Radiation (IR) is a key treatment modality for DIPG, but it provides only temporary relief as the tumor cells develop resistance to radiation. Recently, we and others have shown that inhibition of BMI1 either alone or in combination with radiation attenuates DIPG cell proliferation in vitro...

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書誌詳細
出版年:Neuro Oncol
主要な著者: Balakrishnan, Ilango, Madhavan, Krishna, Pierce, Angela, Dahl, Nathan, Lemma, Rakeb, Fosmire, Susan, Wang, Dong, Prince, Eric, Alimova, Irina, Hashizume, Rintaro, Huellman, Esther, Hawkins, Cynthia, Carcaboso, Angel Montero, Gupta, Nalin, Monje, Michelle, Jones, Keneth, Green, Adam, Foreman, Nicholas, Vibhakar, Rajeev, Venkataraman, Sujatha
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
Abstracts
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011937/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.148
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