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Complexes formed by mutant p53 and their roles in breast cancer

Breast cancer is the most frequently diagnosed malignancy in women, and mutations in the tumor suppressor p53 are commonly detected in the most aggressive subtypes. The majority of TP53 gene alterations are missense substitutions, leading to expression of mutant forms of the p53 protein that are fre...

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Bibliografske podrobnosti
izdano v:Breast Cancer (Dove Med Press)
Main Authors: Bellazzo, Arianna, Sicari, Daria, Valentino, Elena, Del Sal, Giannino, Collavin, Licio
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011883/
https://ncbi.nlm.nih.gov/pubmed/29950894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S145826
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