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Complexes formed by mutant p53 and their roles in breast cancer

Breast cancer is the most frequently diagnosed malignancy in women, and mutations in the tumor suppressor p53 are commonly detected in the most aggressive subtypes. The majority of TP53 gene alterations are missense substitutions, leading to expression of mutant forms of the p53 protein that are fre...

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Detalhes bibliográficos
Publicado no:Breast Cancer (Dove Med Press)
Main Authors: Bellazzo, Arianna, Sicari, Daria, Valentino, Elena, Del Sal, Giannino, Collavin, Licio
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011883/
https://ncbi.nlm.nih.gov/pubmed/29950894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S145826
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