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Complexes formed by mutant p53 and their roles in breast cancer
Breast cancer is the most frequently diagnosed malignancy in women, and mutations in the tumor suppressor p53 are commonly detected in the most aggressive subtypes. The majority of TP53 gene alterations are missense substitutions, leading to expression of mutant forms of the p53 protein that are fre...
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| Veröffentlicht in: | Breast Cancer (Dove Med Press) |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6011883/ https://ncbi.nlm.nih.gov/pubmed/29950894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S145826 |
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