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Mutant p53 as a guardian of the cancer cell

Forty years of research have established that the p53 tumor suppressor provides a major barrier to neoplastic transformation and tumor progression by its unique ability to act as an extremely sensitive collector of stress inputs, and to coordinate a complex framework of diverse effector pathways and...

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Detalles Bibliográficos
Publicado en:Cell Death Differ
Main Authors: Mantovani, Fiamma, Collavin, Licio, Del Sal, Giannino
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329812/
https://ncbi.nlm.nih.gov/pubmed/30538286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0246-9
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