Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants

BACKGROUND: Recent advances in clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) genome editing have led to the use of long single-stranded DNA (lssDNA) molecules for generating conditional mutations. However, there is still limited available data...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Biol
Egile Nagusiak: Codner, Gemma F., Mianné, Joffrey, Caulder, Adam, Loeffler, Jorik, Fell, Rachel, King, Ruairidh, Allan, Alasdair J., Mackenzie, Matthew, Pike, Fran J., McCabe, Christopher V., Christou, Skevoulla, Joynson, Sam, Hutchison, Marie, Stewart, Michelle E., Kumar, Saumya, Simon, Michelle M., Agius, Loranne, Anstee, Quentin M., Volynski, Kirill E., Kullmann, Dimitri M., Wells, Sara, Teboul, Lydia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011369/
https://ncbi.nlm.nih.gov/pubmed/29925374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0530-7
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