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Unsupervised clustering and epigenetic classification of single cells

Characterizing epigenetic heterogeneity at the cellular level is a critical problem in the modern genomics era. Assays such as single cell ATAC-seq (scATAC-seq) offer an opportunity to interrogate cellular level epigenetic heterogeneity through patterns of variability in open chromatin. However, the...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Zamanighomi, Mahdi, Lin, Zhixiang, Daley, Timothy, Chen, Xi, Duren, Zhana, Schep, Alicia, Greenleaf, William J., Wong, Wing Hung
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010417/
https://ncbi.nlm.nih.gov/pubmed/29925875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04629-3
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