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Modeling regulatory network topology improves genome-wide analyses of complex human traits

Genome-wide association studies (GWAS) have cataloged many significant associations between genetic variants and complex traits. However, most of these findings have unclear biological significance, because they often have small effects and occur in non-coding regions. Integration of GWAS with gene...

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Vydáno v:Nat Commun
Hlavní autoři: Zhu, Xiang, Duren, Zhana, Wong, Wing Hung
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121952/
https://ncbi.nlm.nih.gov/pubmed/33990562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22588-0
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