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DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data

Characterizing and interpreting heterogeneous mixtures at the cellular level is a critical problem in genomics. Single-cell assays offer an opportunity to resolve cellular level heterogeneity, e.g., scRNA-seq enables single-cell expression profiling, and scATAC-seq identifies active regulatory eleme...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Zeng, Wanwen, Chen, Xi, Duren, Zhana, Wang, Yong, Jiang, Rui, Wong, Wing Hung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787340/
https://ncbi.nlm.nih.gov/pubmed/31601804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12547-1
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