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Predicting transcription factor binding motifs from DNA-binding domains, chromatin accessibility and gene expression data

Transcription factors (TFs) play crucial roles in regulating gene expression through interactions with specific DNA sequences. Recently, the sequence motif of almost 400 human TFs have been identified using high-throughput SELEX sequencing. However, there remain a large number of TFs (∼800) with no...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zamanighomi, Mahdi, Lin, Zhixiang, Wang, Yong, Jiang, Rui, Wong, Wing Hung
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449588/
https://ncbi.nlm.nih.gov/pubmed/28472398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx358
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