Suppression of CHK1 by ETS family members promotes DNA damage response by-pass and tumorigenesis

The ETS family of transcription factors has been repeatedly implicated in tumorigenesis. In prostate cancer, ETS family members such as ERG, ETV1, ETV4 and ETV5 are frequently overexpressed due to chromosomal translocations, but the molecular mechanisms by which they promote prostate tumorigenesis r...

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Publicado en:Cancer Discov
Autores principales: Lunardi, Andrea, Varmeh, Shohreh, Chen, Ming, Taulli, Riccardo, Guarniero, Jlenia, Ala, Ugo, Seitzer, Nina, Ishikawa, Tomoki, Carver, Brett S., Hobbs, Robin M., Quarantotti, Valentina, Ng, Christopher, Berger, Alice H., Nardella, Caterina, Poliseno, Laura, Montironi, Rodolfo, Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Signoretti, Sabina, Pandolfi, Pier Paolo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010310/
https://ncbi.nlm.nih.gov/pubmed/25653093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-1050
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