Suppression of CHK1 by ETS family members promotes DNA damage response by-pass and tumorigenesis

The ETS family of transcription factors has been repeatedly implicated in tumorigenesis. In prostate cancer, ETS family members such as ERG, ETV1, ETV4 and ETV5 are frequently overexpressed due to chromosomal translocations, but the molecular mechanisms by which they promote prostate tumorigenesis r...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Lunardi, Andrea, Varmeh, Shohreh, Chen, Ming, Taulli, Riccardo, Guarniero, Jlenia, Ala, Ugo, Seitzer, Nina, Ishikawa, Tomoki, Carver, Brett S., Hobbs, Robin M., Quarantotti, Valentina, Ng, Christopher, Berger, Alice H., Nardella, Caterina, Poliseno, Laura, Montironi, Rodolfo, Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Signoretti, Sabina, Pandolfi, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010310/
https://ncbi.nlm.nih.gov/pubmed/25653093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-1050
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