p73α Regulation by Chk1 in Response to DNA Damage

The checkpoint kinase 1 (Chk1) is an essential component of the DNA damage checkpoint. Previous studies have demonstrated an indispensable role for the p53-related transcription factor p73α in DNA damage-induced apoptosis. Here, we provide evidence that p73α is a target of Chk1. We found that endoge...

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Bibliografiske detaljer
Main Authors: Gonzalez, Susana, Prives, Carol, Cordon-Cardo, Carlos
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC262369/
https://ncbi.nlm.nih.gov/pubmed/14585975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8161-8171.2003
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