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Direct Access to Highly Functionalized Heterocycles through the Condensation of Cyclic Imines and α-Oxoesters
A facile, gram-scale preparation of 2-hydroxy-5,6,7,7a-tetrahydro-3H-pyrrolizin-3-ones and 2-hydroxy-6,7,8,8a-tetrahydroindolizin-3(5H)-ones from a condensation cyclization of α-oxoesters with five- and six-membered cyclic imines, respectively, is reported. This transformation enables a concise, thr...
Enregistré dans:
| Publié dans: | J Org Chem |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6008790/ https://ncbi.nlm.nih.gov/pubmed/29206454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b02572 |
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