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Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis

The 3-thiazolidine ring represents an important structural motif in life sciences molecules. However, up to now reduction of 3-thiazolines as an attractive approach failed by means of nearly all chemical reduction technologies for imines. Thus, the development of an efficient general and enantiosele...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zumbrägel, Nadine, Merten, Christian, Huber, Stefan M., Gröger, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955971/
https://ncbi.nlm.nih.gov/pubmed/29769523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03841-5
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