Optimized synthesis and antiproliferative activity of desTHPdactylolides

Dactylolide and certain analogues are attractive targets for study due to their structural resemblance to zampanolide, a very promising anticancer lead compound and a unique covalent-binding microtubule stabilizing agent. The primary goal of this project is identification and synthesis of simplified...

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Gepubliceerd in:Bioorg Med Chem
Hoofdauteurs: Chen, Guanglin, Wang, Rubing, Vue, Bao, Patanapongpibul, Manee, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, White, James D., Chen, Qiao-Hong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008235/
https://ncbi.nlm.nih.gov/pubmed/29784275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.05.026
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