Asymmetric 1,5-Diarylpenta-1,4-dien-3-ones: Antiproliferative Activity in Prostate Epithelial Cell Models and Pharmacokinetic Studies

To further engineer dienones with optimal combinations of potency and bioavailability, thirty-four asymmetric 1,5-diarylpenta-1,4-dien-3-ones (25–58) have been designed and synthesized for the evaluation of their in vitro anti-proliferative activity in three human prostate cancer cell lines and one...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Zhang, Xiaojie, Guo, Shanchun, Chen, Chengsheng, Perez, German Ruiz, Zhang, Changde, Patanapongpibul, Manee, Subrahmanyam, Nithya, Wang, Rubing, Keith, Joshua, Chen, Guanglin, Dong, Yan, Zhang, Qiang, Zhong, Qiu, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548007/
https://ncbi.nlm.nih.gov/pubmed/28601720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.05.062
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados