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Synthesis and antiproliferative evaluation of new zampanolide mimics
(–)–Zampanolide is a marine microtubule-stabilizing macrolide that has been shown by in vitro experiments to be a promising anticancer lead compound. Through its unique covalent-binding with β-tubulin, zampanolide exhibits cytotoxic potency towards multi-drug resistant cancer cells that is superior...
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| Publicado no: | Org Biomol Chem |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6555766/ https://ncbi.nlm.nih.gov/pubmed/30924817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob00556k |
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