Loading...

Cystamine and Disulfiram Inhibit Human Transglutaminase 2 via an Oxidative Mechanism

The catalytic activity of transglutaminase 2 (TG2), a ubiquitously expressed mammalian enzyme, is regulated by multiple post-translational mechanisms. Because elevated activity of TG2 in the extracellular matrix is associated with organ-specific diseases such as celiac disease and renal fibrosis, th...

Full description

Saved in:
Bibliographic Details
Published in:Biochemistry
Main Authors: Palanski, Brad A., Khosla, Chaitan
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008213/
https://ncbi.nlm.nih.gov/pubmed/29570977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00204
Tags: Add Tag
No Tags, Be the first to tag this record!