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Endoplasmic reticulum–resident protein 57 (ERp57) oxidatively inactivates human transglutaminase 2

Transglutaminase 2 (TG2) is a ubiquitously expressed, intracellular as well as extracellular protein with multiple modes of post-translational regulation, including an allosteric disulfide bond between Cys-370–Cys-371 that renders the enzyme inactive in the extracellular matrix. Although recent stud...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yi, Michael C., Melkonian, Arek V., Ousey, James A., Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827427/
https://ncbi.nlm.nih.gov/pubmed/29305423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001382
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