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ERp57 Modulates STAT3 Signaling from the Lumen of the Endoplasmic Reticulum

ERp57 is an endoplasmic reticulum (ER) resident thiol disulfide oxidoreductase. Using the gene trap technique, we created a ERp57-deficient mouse model. Targeted deletion of the Pdia3 gene, which encodes ERp57, in mice is embryonic lethal at embryonic day (E) 13.5. β-Galactosidase reporter gene anal...

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Bibliografske podrobnosti
Main Authors: Coe, Helen, Jung, Joanna, Groenendyk, Jody, Prins, Daniel, Michalak, Marek
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825467/
https://ncbi.nlm.nih.gov/pubmed/20022947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.054015
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