Modulation of STIM1 and capacitative Ca(2+) entry by the endoplasmic reticulum luminal oxidoreductase ERp57

STIM1 is an endoplasmic reticulum (ER) membrane Ca(2+) sensor responsible for activation of store-operated Ca(2+) influx. We discovered that STIM1 oligomerization and store-operated Ca(2+) entry (SOC) are modulated by the ER oxidoreductase ERp57. ERp57 interacts with the ER luminal domain of STIM1,...

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Bibliographische Detailangaben
Hauptverfasser: Prins, Daniel, Groenendyk, Jody, Touret, Nicolas, Michalak, Marek
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Scientific Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207099/
https://ncbi.nlm.nih.gov/pubmed/21941299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.173
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