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The antihelminthic moxidectin enhances tonic GABA currents in rodent hippocampal pyramidal neurons

Macrocyclic lactones (MLs) are commonly used treatments for parasitic worm and insect infections in humans, livestock, and companion animals. MLs target the invertebrate glutamate-activated chloride channel that is not present in vertebrates. MLs are not entirely inert in vertebrates, though; they h...

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Pubblicato in:J Neurophysiol
Autori principali: Spampanato, Jay, Gibson, Anne, Dudek, F. Edward
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008095/
https://ncbi.nlm.nih.gov/pubmed/29364072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00587.2017
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