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The antihelminthic moxidectin enhances tonic GABA currents in rodent hippocampal pyramidal neurons

Macrocyclic lactones (MLs) are commonly used treatments for parasitic worm and insect infections in humans, livestock, and companion animals. MLs target the invertebrate glutamate-activated chloride channel that is not present in vertebrates. MLs are not entirely inert in vertebrates, though; they h...

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Vydáno v:J Neurophysiol
Hlavní autoři: Spampanato, Jay, Gibson, Anne, Dudek, F. Edward
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008095/
https://ncbi.nlm.nih.gov/pubmed/29364072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00587.2017
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