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The antihelminthic moxidectin enhances tonic GABA currents in rodent hippocampal pyramidal neurons

Macrocyclic lactones (MLs) are commonly used treatments for parasitic worm and insect infections in humans, livestock, and companion animals. MLs target the invertebrate glutamate-activated chloride channel that is not present in vertebrates. MLs are not entirely inert in vertebrates, though; they h...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Spampanato, Jay, Gibson, Anne, Dudek, F. Edward
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008095/
https://ncbi.nlm.nih.gov/pubmed/29364072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00587.2017
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