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Downregulation of tonic GABA currents following epileptogenic stimulation of rat hippocampal cultures
Deficits in GABAergic inhibitory transmission are a hallmark of temporal lobe epilepsy and have been replicated in animal and tissue culture models of epilepsy. GABAergic inhibition comprises phasic and tonic inhibition that is mediated by synaptic and extrasynaptic GABA(A) receptors, respectively....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890447/ https://ncbi.nlm.nih.gov/pubmed/16990405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.113134 |
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