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Downregulation of tonic GABA currents following epileptogenic stimulation of rat hippocampal cultures

Deficits in GABAergic inhibitory transmission are a hallmark of temporal lobe epilepsy and have been replicated in animal and tissue culture models of epilepsy. GABAergic inhibition comprises phasic and tonic inhibition that is mediated by synaptic and extrasynaptic GABA(A) receptors, respectively....

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Autori principali: Qi, Jin-shun, Yao, Jun, Fang, Cheng, Luscher, Bernhard, Chen, Gong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890447/
https://ncbi.nlm.nih.gov/pubmed/16990405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.113134
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