Gene Therapy for Osteoarthritis: Pharmacokinetics of Intra-Articular Self-Complementary Adeno-Associated Virus Interleukin-1 Receptor Antagonist Delivery in an Equine Model

Toward the treatment of osteoarthritis (OA), the authors have been investigating self-complementary adeno-associated virus (scAAV) for intra-articular delivery of therapeutic gene products. As OA frequently affects weight-bearing joints, pharmacokinetic studies of scAAV gene delivery were performed...

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書誌詳細
出版年:Hum Gene Ther Clin Dev
主要な著者: Watson Levings, Rachael S., Broome, Ted A., Smith, Andrew D., Rice, Brett L., Gibbs, Eric P., Myara, David A., Hyddmark, E. Viktoria, Nasri, Elham, Zarezadeh, Ali, Levings, Padraic P., Lu, Yuan, White, Margaret E., Dacanay, E. Anthony, Foremny, Gregory B., Evans, Christopher H., Morton, Alison J., Winter, Mathew, Dark, Michael J., Nickerson, David M., Colahan, Patrick T., Ghivizzani, Steven C.
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2018
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007808/
https://ncbi.nlm.nih.gov/pubmed/29869540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2017.142
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