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Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells
Combinational anticancer therapy demonstrates increased efficiency, as it targets different cell-survival mechanisms and allows the decrease of drug dosages that are often toxic to normal cells. Inhibitors of the heat shock response (HSR) are known to reduce the efficiency of proteostasis mechanisms...
Zapisane w:
| Wydane w: | Oncotarget |
|---|---|
| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Impact Journals LLC
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6007471/ https://ncbi.nlm.nih.gov/pubmed/29930764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25545 |
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