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Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates

The vast majority of neurodegenerative pathologies stem from the formation of toxic oligomers and aggregates composed of wrongly folded proteins. These protein complexes can be released from pathogenic cells and enthralled by other cells, causing the formation of new aggregates in a prion-like manne...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Principais autores: Lazarev, Vladimir F., Mikhaylova, Elena R., Guzhova, Irina V., Margulis, Boris A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433261/
https://ncbi.nlm.nih.gov/pubmed/28559794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00277
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