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Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone Hsp70

The response of cancer cells to apoptosis-inducing agents can be characterized by 2 opposing factors, the proapoptotic caspase cascade and the antiapoptotic stress protein Hsp70. We show here that these factors interact in U-937 leukemia cells induced to apoptosis with anticancer drugs, etoposide an...

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Bibliografiske detaljer
Main Authors: Komarova, Elena Yu., Afanasyeva, Elena A., Bulatova, Marina M., Cheetham, Michael E., Margulis, Boris A., Guzhova, Irina V.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Stress Society International 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065285/
https://ncbi.nlm.nih.gov/pubmed/15544164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-27R1.1
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