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Histone H3 lysine 36 methyltransferase mobilizes NER factors to regulate tolerance against alkylation damage in fission yeast

The Set2 methyltransferase and its target, histone H3 lysine 36 (H3K36), affect chromatin architecture during the transcription and repair of DNA double-stranded breaks. Set2 also confers resistance against the alkylating agent, methyl methanesulfonate (MMS), through an unknown mechanism. Here, we s...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Lim, Kim Kiat, Nguyen, Thi Thuy Trang, Li, Adelicia Yongling, Yeo, Yee Phan, Chen, Ee Sin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007430/
https://ncbi.nlm.nih.gov/pubmed/29635344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky245
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