Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolic pathway, and its loss of function through polymorphisms is often associated with human conditions, including cancer, congenital heart disease, and Down syndrome. MTHFR is also required in the maintenance of heterochr...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Lim, Kim Kiat, Teo, Hwei Yee, Tan, Yuan Yee, Zeng, Yi Bing, Lam, Ulysses Tsz Fung, Choolani, Mahesh, Chen, Ee Sin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827777/
https://ncbi.nlm.nih.gov/pubmed/33440639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020639
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