Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolic pathway, and its loss of function through polymorphisms is often associated with human conditions, including cancer, congenital heart disease, and Down syndrome. MTHFR is also required in the maintenance of heterochr...

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Udgivet i:Int J Mol Sci
Main Authors: Lim, Kim Kiat, Teo, Hwei Yee, Tan, Yuan Yee, Zeng, Yi Bing, Lam, Ulysses Tsz Fung, Choolani, Mahesh, Chen, Ee Sin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827777/
https://ncbi.nlm.nih.gov/pubmed/33440639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020639
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