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Histone H3 lysine 36 methyltransferase mobilizes NER factors to regulate tolerance against alkylation damage in fission yeast

The Set2 methyltransferase and its target, histone H3 lysine 36 (H3K36), affect chromatin architecture during the transcription and repair of DNA double-stranded breaks. Set2 also confers resistance against the alkylating agent, methyl methanesulfonate (MMS), through an unknown mechanism. Here, we s...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lim, Kim Kiat, Nguyen, Thi Thuy Trang, Li, Adelicia Yongling, Yeo, Yee Phan, Chen, Ee Sin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007430/
https://ncbi.nlm.nih.gov/pubmed/29635344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky245
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