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A human nuclease specific for G4 DNA

We have identified a human nuclease that specifically cleaves four-stranded DNA stabilized by G quartets (G4 DNA). This nuclease, GQN1 (G quartet nuclease 1), cuts within the single-stranded region 5′ of the barrel formed by stacked G quartets. GQN1 does not cleave duplex or single-stranded DNA, Hol...

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Hlavní autoři: Sun, Hui, Yabuki, Akiko, Maizels, Nancy
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC60073/
https://ncbi.nlm.nih.gov/pubmed/11675489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231479198
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