A human nuclease specific for G4 DNA

We have identified a human nuclease that specifically cleaves four-stranded DNA stabilized by G quartets (G4 DNA). This nuclease, GQN1 (G quartet nuclease 1), cuts within the single-stranded region 5′ of the barrel formed by stacked G quartets. GQN1 does not cleave duplex or single-stranded DNA, Hol...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sun, Hui, Yabuki, Akiko, Maizels, Nancy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11675489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231479198
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