Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer

PARP inhibitors have been widely tested in clinical trials, especially for the treatment of breast cancer and ovarian cancer, and were shown to be highly successful. Because PARP primarily functions in sensing and repairing DNA strand breaks, the therapeutic effect of PARP inhibition is generally be...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Redox Biol
Päätekijät: Hou, Dong, Liu, Zhaojian, Xu, Xiuhua, Liu, Qiao, Zhang, Xiyu, Kong, Beihua, Wei, Jian-Jun, Gong, Yaoqin, Shao, Changshun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2018
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006521/
https://ncbi.nlm.nih.gov/pubmed/29684820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.03.016
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