Population pharmacokinetics of voriconazole and CYP2C19 polymorphisms for optimizing dosing regimens in renal transplant recipients

AIMS: The aims of the present study were to characterize the pharmacokinetics of voriconazole in renal transplant recipients and to identify factors significantly affecting pharmacokinetic parameters. We also aimed to explore the optimal dosing regimens for patients who developed invasive fungal inf...

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Publicado en:Br J Clin Pharmacol
Autores principales: Lin, Xiao‐bin, Li, Zi‐wei, Yan, Miao, Zhang, Bi‐kui, Liang, Wu, Wang, Feng, Xu, Ping, Xiang, Da‐xiong, Xie, Xu‐biao, Yu, Shao‐jie, Lan, Gong‐bin, Peng, Feng‐hua
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005582/
https://ncbi.nlm.nih.gov/pubmed/29607533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13595
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