Effects of erythromycin on voriconazole pharmacokinetics and association with CYP2C19 polymorphism

PURPOSE: To assess the impacts of erythromycin on the pharmacokinetics of voriconazole and its association with CYP2C19 genotypes in healthy Chinese male subjects. METHODS: A single-center, open, crossover clinical study with two treatment phases was carried out. Eighteen healthy male volunteers, in...

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Bibliographic Details
Main Authors: Shi, Hui-Yan, Yan, Jin, Zhu, Wen-Hui, Yang, Guo-Ping, Tan, Zhi-Rong, Wu, Wei-Hua, Zhou, Gan, Chen, Xiao-Ping, Ouyang, Dong-Sheng
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2010
Subjects:
Pharmacokinetics and Disposition
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957581/
https://ncbi.nlm.nih.gov/pubmed/20669013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-010-0869-3
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