Impact of CYP2C19 Genotype and Liver Function on Voriconazole Pharmacokinetics in Renal Transplant Recipients

BACKGROUND: Invasive fungal infection (IFI) is one of the leading causes of early death after renal transplantation. Voriconazole (VRC) is the first-line drug of IFI. Because of the large inter- and intraindividual variability in VRC plasma concentrations and the narrow therapeutic window for treati...

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Dettagli Bibliografici
Pubblicato in:Ther Drug Monit
Autori principali: Li, Zi-Wei, Peng, Feng-Hua, Yan, Miao, Liang, Wu, Liu, Xiao-Lei, Wu, Yan-Qin, Lin, Xiao-Bin, Tan, Sheng-Lan, Wang, Feng, Xu, Ping, Fang, Ping-Fei, Liu, Yi-Ping, Xiang, Da-Xiong, Zhang, Bi-Kui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Therapeutic Drug Monitoring 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538305/
https://ncbi.nlm.nih.gov/pubmed/28604474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000425
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