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Population pharmacokinetics of voriconazole and CYP2C19 polymorphisms for optimizing dosing regimens in renal transplant recipients

AIMS: The aims of the present study were to characterize the pharmacokinetics of voriconazole in renal transplant recipients and to identify factors significantly affecting pharmacokinetic parameters. We also aimed to explore the optimal dosing regimens for patients who developed invasive fungal inf...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Lin, Xiao‐bin, Li, Zi‐wei, Yan, Miao, Zhang, Bi‐kui, Liang, Wu, Wang, Feng, Xu, Ping, Xiang, Da‐xiong, Xie, Xu‐biao, Yu, Shao‐jie, Lan, Gong‐bin, Peng, Feng‐hua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005582/
https://ncbi.nlm.nih.gov/pubmed/29607533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13595
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