Targeting of TAM Receptors Ameliorates Fibrotic Mechanisms in Idiopathic Pulmonary Fibrosis

Rationale: Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant lung remodeling, which progressively abolishes lung function in an RTK (receptor tyrosine kinase)–dependent manner. Gas6 (growth arrest–specific 6) ligand, Tyro3 (TYRO3 protein tyrosine kinase 3), and Axl (anexelekto) RTK ex...

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Bibliografische gegevens
Gepubliceerd in:Am J Respir Crit Care Med
Hoofdauteurs: Espindola, Milena S., Habiel, David M., Narayanan, Rohan, Jones, Isabelle, Coelho, Ana L., Murray, Lynne A., Jiang, Dianhua, Noble, Paul W., Hogaboam, Cory M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2018
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005556/
https://ncbi.nlm.nih.gov/pubmed/29634284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201707-1519OC
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