DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis

BACKGROUND: Recent studies have highlighted the contribution of senescent mesenchymal and epithelial cells in Idiopathic Pulmonary Fibrosis (IPF), but little is known regarding the molecular mechanisms that regulate the accumulation of senescent cells in this disease. Therefore, we addressed the hyp...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Habiel, David M., Hohmann, Miriam S., Espindola, Milena S., Coelho, Ana Lucia, Jones, Isabelle, Jones, Heather, Carnibella, Richard, Pinar, Isaac, Werdiger, Freda, Hogaboam, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716822/
https://ncbi.nlm.nih.gov/pubmed/31464599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-019-0922-7
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