DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis

BACKGROUND: Recent studies have highlighted the contribution of senescent mesenchymal and epithelial cells in Idiopathic Pulmonary Fibrosis (IPF), but little is known regarding the molecular mechanisms that regulate the accumulation of senescent cells in this disease. Therefore, we addressed the hyp...

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Publicat a:BMC Pulm Med
Autors principals: Habiel, David M., Hohmann, Miriam S., Espindola, Milena S., Coelho, Ana Lucia, Jones, Isabelle, Jones, Heather, Carnibella, Richard, Pinar, Isaac, Werdiger, Freda, Hogaboam, Cory M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716822/
https://ncbi.nlm.nih.gov/pubmed/31464599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-019-0922-7
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