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Modeling Idiopathic Pulmonary Fibrosis in Humanized Severe Combined Immunodeficient Mice
Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease of unknown etiopathogenesis with limited therapeutic options. IPF is characterized by an abundance of fibroblasts and loss of epithelial progenitors, which cumulates in unrelenting fibrotic lung remodeling and loss of normal oxygenation....
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| Publicado no: | Am J Pathol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5954978/ https://ncbi.nlm.nih.gov/pubmed/29378172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.020 |
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