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Modeling Idiopathic Pulmonary Fibrosis in Humanized Severe Combined Immunodeficient Mice
Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease of unknown etiopathogenesis with limited therapeutic options. IPF is characterized by an abundance of fibroblasts and loss of epithelial progenitors, which cumulates in unrelenting fibrotic lung remodeling and loss of normal oxygenation....
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| Опубликовано в: : | Am J Pathol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5954978/ https://ncbi.nlm.nih.gov/pubmed/29378172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.020 |
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