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Modeling Idiopathic Pulmonary Fibrosis in Humanized Severe Combined Immunodeficient Mice

Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease of unknown etiopathogenesis with limited therapeutic options. IPF is characterized by an abundance of fibroblasts and loss of epithelial progenitors, which cumulates in unrelenting fibrotic lung remodeling and loss of normal oxygenation....

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Bibliografske podrobnosti
izdano v:Am J Pathol
Main Authors: Habiel, David M., Espindola, Milena S., Coelho, Ana L., Hogaboam, Cory M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954978/
https://ncbi.nlm.nih.gov/pubmed/29378172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.020
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