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Modeling Idiopathic Pulmonary Fibrosis in Humanized Severe Combined Immunodeficient Mice

Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease of unknown etiopathogenesis with limited therapeutic options. IPF is characterized by an abundance of fibroblasts and loss of epithelial progenitors, which cumulates in unrelenting fibrotic lung remodeling and loss of normal oxygenation....

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發表在:Am J Pathol
Main Authors: Habiel, David M., Espindola, Milena S., Coelho, Ana L., Hogaboam, Cory M.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954978/
https://ncbi.nlm.nih.gov/pubmed/29378172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.020
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